Membrane chromatography


Membranes with chromatographic characteristics are increasingly used in biotechnology in the separation of biomolecules such as proteins and biological substances such as monoclonal antibodies. The advantage over chromatographic methods used to date lie in the higher flow rate and ensuing improved separation efficiency.

One disadvantage of chromatographic separation has not yet been solved by using chromatographic membranes. Removing (impurities) or recovering (biological agents) the adsorbed biomolecules from the carrier material requires the use of high concentrations of salt or changing the pH value. 

i3 Membrane has developed a method which remedies the disadvantage outlined above. Thanks to ultra-thin metal coatings on the membrane and the application of a defined voltage, biomolecules adsorbed by electric fields can be fully desorbed at any time. Without using any chemicals and within seconds.

i3 Membrane has therefore succeeded in digitizing modern separation methods which represents the dawn of a new era in digital membrane chromatography.