Particle analytics

with gold-coated track-etched filters

Particles can interfere with the effect of drugs

Particle analysis is essential in quality control during the production of drugs and excipients and in research and development of new pharmaceuticals and auxiliary chemicals. Particle size and particle shape are of interest because the biopharmaceutical product particle size can influence a product in two ways. These particles are considered to be indicators of contamination and they can disrupt the action of drugs. In some cases, pharmaceutical materials and auxiliary chemicals are contaminated with particles from the raw material; in other cases, the particles can come from parts of the production equipment, packaging, machinery or process. They may be produced due to friction of moving parts such as valves in transporting and filling equipment.

Highest standards of cleanliness for automotive production

Particle analysis is nevertheless also very important in automobile production. Here, too, the highest standards of cleanliness must be established. Compliance with these standards begins right back with the components being used, which are extremely sensitive and are exposed to numerous contamination risks during production. Keeping these risks as low as possible takes top priority. Compliance with all requirements, norms and standards is regularly checked using special tests of cleanliness for quality assurance in several analytical stages.

Optimum reflection due to homogeneous gold coating

i3 Membrane has developed special membranes for applications in the pharmaceutical, chemical and automobile industries. The track-etched filters, which are coated with gold by vapor deposition, deliver optimal reflection in Fourier transform infrared (FTIR) microscopy and Raman spectroscopy. They make a suitable conductive substrate for imaging with scanning electron microscopy (EDX/WDX).

The different pore sizes of the polyester membranes allow the filtration of all organic and inorganic particles. The filters are an indispensable tool for many companies in the pharmaceutical industry, the chemical industry and the automobile industry.

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Publications

  • 15.06.2022

    Particle analytics (German Edition) with gold-coated track-etched filters

    i3 Membrane has developed special membranes for applications in industry sectors, such as the pharmaceutical, cosmetics and the food industry, as well as the chemical and the automobile industry.

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  • 20.05.2019

    Gold-coated PET core pore filters fixed in an aluminum ring (German Edition) i3 TrackPor R for particle analysis

    Efficient and state-of-the-art identification and characterization of micro- and nanoparticles in liquids.

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  • 15.04.2019

    i3 TrackPor M (German Edition) Ready-to-use disposable monitor for asbestos analysis

    Facilitates the thanks to the membrane already sputtered with gold for examination of asbestos particles in the air.

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  • 07.02.2019

    i3 FlexiPor membranes (German Edition) for sterile filtration and tissue engineering

    The use of alumina membranes is characterized by low adsorption, high chemical inertness and the exclusion of extractables.

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  • 04.02.2019

    Gold-coated track-etched membranes (German Edition) i3 TrackPor for asbestos and particle analysis

    Easy particle adhesion due to extra-flat surface and tunnel-shaped pore-vaporized arrangement. Track-etched membranes are produced in a three-step process.

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Linking knowledge

As your companion for life science filtration, we support you with new, effective separation technologies in the Lab/Pharma, Medical and Biotech fields.

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Europe
i3 Membrane GmbH
Theodorstraße 41 P
22761 Hamburg
Germany
Americas
i3 Membrane Corporation
13801 Reese Blvd West. Ste 310
Huntersville, NC. 28078
USA